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Pax6 is required intrinsically by thalamic progenitors for the normal molecular patterning of thalamic neurons but not the growth and guidance of their axons

BACKGROUND: In mouse embryos, the Pax6 transcription factor is expressed in the progenitors of thalamic neurons but not in thalamic neurons themselves. Its null-mutation causes early mis-patterning of thalamic progenitors. It is known that thalamic neurons generated by Pax6(−/−) progenitors do not d...

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Detalhes bibliográficos
Publicado no:Neural Dev
Main Authors: Clegg, James M., Li, Ziwen, Molinek, Michael, Caballero, Isabel Martín, Manuel, Martine N., Price, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4628245/
https://ncbi.nlm.nih.gov/pubmed/26520399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13064-015-0053-7
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