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Next-generation sequencing identifies altered whole blood microRNAs in neuromyelitis optica spectrum disorder which may permit discrimination from multiple sclerosis

BACKGROUND: Neuromyelitis optica spectrum disorder (NMOSD) and multiple sclerosis (MS) have a similar clinical phenotype but represent distinct diseases, requiring different therapies. MicroRNAs (miRNAs) are short non-coding RNAs whose expression profiles can serve as diagnostic biomarkers and which...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Keller, Andreas, Leidinger, Petra, Meese, Eckart, Haas, Jan, Backes, Christina, Rasche, Ludwig, Behrens, Janina R., Pfuhl, Catherina, Wakonig, Katharina, Gieß, René M., Jarius, Sven, Meder, Benjamin, Bellmann-Strobl, Judith, Paul, Friedemann, Pache, Florence C., Ruprecht, Klemens
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4628234/
https://ncbi.nlm.nih.gov/pubmed/26521232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0418-1
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