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Development and validation of a LC–MS/MS method for quantification of hetrombopag for pharmacokinetics study

Hetrombopag as the derivative of ethylidene hydrazine carboxamide was recently developed into a novel patented non-peptide thrombopoietin mimetic and thrombopoietin receptor agonist to treat idiopathic thrombocytopenic purpura. To study the pharmacokinetics of hetrombopag, a highly sensitive, rapid...

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Publicado en:Springerplus
Autores principales: Chen, Tao, Chen, Zhonghua, Zhang, Suxing, Zhang, Kezhi, Wang, Laiyou
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer International Publishing 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4628022/
https://ncbi.nlm.nih.gov/pubmed/26543786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40064-015-1446-0
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