Strain Improvement of Streptomyces xanthochromogenes RIA 1098 for Enhanced Pravastatin Production at High Compactin Concentrations

Pravastatin is one of the most popular cholesterol-lowering drugs. Its industrial production represents a two-stage process including the microbial production of compactin and its further biocatalytic conversion to pravastatin. To increase a conversion rate, a higher compactin content in fermentatio...

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Detalhes bibliográficos
Publicado no:Indian J Microbiol
Main Authors: Dzhavakhiya, Vakhtang V., Voinova, Tatiana M., Glagoleva, Elena V., Petukhov, Dmitry V., Ovchinnikov, Alexander I., Kartashov, Maksim I., Kuznetsov, Boris B., Skryabin, Konstantin G.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer India 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627957/
https://ncbi.nlm.nih.gov/pubmed/26543270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12088-015-0537-5
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