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Right Ventricular Adaptation Is Associated with the Glu298Asp Variant of the NOS3 Gene in Elite Athletes

Nitric oxide (NO), an important endogenous pulmonary vasodilator is synthetized by the endothelial NO synthase (NOS3). Reduced NO bioavailability and thus the Glu298Asp polymorphism of NOS3 may enhance right ventricular (RV) afterload and hypertrophic remodeling and influence athletic performance. T...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Szelid, Zsolt, Lux, Árpád, Kolossváry, Márton, Tóth, Attila, Vágó, Hajnalka, Lendvai, Zsuzsanna, Kiss, Loretta, Maurovich-Horvat, Pál, Bagyura, Zsolt, Merkely, Béla
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627801/
https://ncbi.nlm.nih.gov/pubmed/26517550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141680
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