Identification and Functional Studies of Regulatory Variants Responsible for the Association of NRG3 with a Delusion Phenotype in Schizophrenia

We previously reported a genetic linkage for schizophrenia (SZ; nonparametric linkage score of 4.27) at 10q22 in an Ashkenazi Jewish (AJ) population. In follow-up fine-mapping, we found strong evidence for an association between 3 intronic single nucleotide variants (SNVs) in the 5′ end of neureguli...

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Detalhes bibliográficos
Publicado no:Mol Neuropsychiatry
Main Authors: Zeledón, Mariela, Eckart, Nicole, Taub, Margaret, Vernon, Hilary, Szymanski, Megan, Wang, Ruihua, Chen, Pei-Lung, Nestadt, Gerry, McGrath, John A., Sawa, Akira, Pulver, Ann E., Avramopoulos, Dimitrios, Valle, David
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2015
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627703/
https://ncbi.nlm.nih.gov/pubmed/26528484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000371518
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