Saposin C Coupled Lipid Nanovesicles Enable Cancer-Selective Optical and Magnetic Resonance Imaging

PURPOSE: Nanovesicles composed of the phospholipid dioleylphosphatidylserine (DOPS) and a fusogenic protein, saposin C (SapC), selectively target and induce apoptotic cell death in a variety of human cancer cells in vitro and in vivo. We tested whether such tumor-homing nanovesicles are capable of d...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Imaging Biol
Prif Awduron: Kaimal, Vinod, Chu, Zhengtao, Mahller, Yonatan Y., Papahadjopoulos-Sternberg, Brigitte, Cripe, Timothy P., Holland, Scott K., Qi, Xiaoyang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627685/
https://ncbi.nlm.nih.gov/pubmed/20838909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-010-0417-7
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