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A perfusion-capable microfluidic bioreactor for assessing microbial heterologous protein production

We present an integrated microfluidic bioreactor for fully continuous perfusion cultivation of suspended microbial cell cultures. This system allowed continuous and stable heterologous protein expression by sustaining the cultivation of Pichia pastoris over 11 days. This technical capability also al...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Lab Chip
Päätekijät: Mozdzierz, Nicholas J., Love, Kerry R., Lee, Kevin S., Lee, Harry L. T., Shah, Kartik A., Ram, Rajeev J., Love, J. Christopher
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627644/
https://ncbi.nlm.nih.gov/pubmed/26055071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5lc00443h
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