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Temporal cAMP Signaling Selectivity by Natural and Synthetic MC4R Agonists
The melanocortin-4 receptor (MC4R) is a G protein-coupled receptor expressed in the brain, where it controls energy balance through pathways including α-melanocyte-stimulating hormone (α-MSH)-dependent signaling. We have reported that the MC4R can exist in an active conformation that signals constit...
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| Опубликовано в: : | Mol Endocrinol |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Endocrine Society
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4627605/ https://ncbi.nlm.nih.gov/pubmed/26418335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2015-1071 |
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