Temporal cAMP Signaling Selectivity by Natural and Synthetic MC4R Agonists

The melanocortin-4 receptor (MC4R) is a G protein-coupled receptor expressed in the brain, where it controls energy balance through pathways including α-melanocyte-stimulating hormone (α-MSH)-dependent signaling. We have reported that the MC4R can exist in an active conformation that signals constit...

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Detaylı Bibliyografya
Yayımlandı:Mol Endocrinol
Asıl Yazarlar: Molden, Brent M., Cooney, Kimberly A., West, Kirk, Van Der Ploeg, Lex H. T., Baldini, Giulia
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Endocrine Society 2015
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627605/
https://ncbi.nlm.nih.gov/pubmed/26418335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2015-1071
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