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JAK2 inhibition has different therapeutic effects according to myeloproliferative neoplasm development in mice

JAK2 inhibition therapy is used to treat patients suffering from myeloproliferative neoplasms (MPN). Conflicting data on this therapy are reported possibly linked to the types of inhibitors or disease type. Therefore, we decided to compare in mice the effect of a JAK2 inhibitor, Fedratinib, in MPN m...

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Dades bibliogràfiques
Publicat a:J Cell Mol Med
Autors principals: Debeurme, Franck, Lacout, Catherine, Moratal, Claudine, Bagley, Rebecca G, Vainchenker, William, Adrian, Francisco, Villeval, Jean-Luc
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons, Ltd 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627562/
https://ncbi.nlm.nih.gov/pubmed/26176817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12608
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