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Intravenous Artesunate for the Treatment of Severe and Complicated Malaria in the United States: Clinical Use under an Investigational New Drug Protocol

BACKGROUND: Quinidine gluconate, the only FDA-approved treatment for life-threatening malaria in the United States, has a problematic safety profile and is often unavailable in hospitals. OBJECTIVE: Assess the safety and clinical benefit of intravenous artesunate as a quinidine alternative DESIGN: R...

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Publicat a:Ann Intern Med
Autors principals: Twomey, Patrick S., Smith, Bryan L., McDermott, Cathy, Marino, Anne, McCarthy, William, Kachur, S. Patrick, Ransom, Janet, Arguin, Paul M.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627466/
https://ncbi.nlm.nih.gov/pubmed/26301474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7326/M15-0910
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