A Modeling and Simulation Framework for Adverse Events in Erlotinib-Treated Non-Small-Cell Lung Cancer Patients

Treatment with erlotinib, an epidermal growth factor receptor tyrosine kinase inhibitor used for treating non-small-cell lung cancer (NSCLC) and other cancers, is frequently associated with adverse events (AE). We present a modeling and simulation framework for the most common erlotinib-induced AE,...

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Detalhes bibliográficos
Publicado no:AAPS J
Main Authors: Suleiman, Ahmed Abbas, Frechen, Sebastian, Scheffler, Matthias, Zander, Thomas, Nogova, Lucia, Kocher, Martin, Jaehde, Ulrich, Wolf, Jürgen, Fuhr, Uwe
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627460/
https://ncbi.nlm.nih.gov/pubmed/26286677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-015-9815-8
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