Exosomes derived from miR-122-modified adipose tissue-derived MSCs increase chemosensitivity of hepatocellular carcinoma

BACKGROUND: Hepatocellular carcinoma (HCC) displays high resistance to conventional chemotherapy. Considering that microRNA-122 (miR-122) performs an essential function to promote chemosensitivity of HCC cells, an effective vehicle-mediated miR-122 delivery may represent a promising strategy for HCC...

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Detalhes bibliográficos
Publicado no:J Hematol Oncol
Main Authors: Lou, Guohua, Song, Xiuli, Yang, Fan, Wu, Shanshan, Wang, Jing, Chen, Zhi, Liu, Yanning
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627430/
https://ncbi.nlm.nih.gov/pubmed/26514126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-015-0220-7
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