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Neuroinflammatory paradigms in lysosomal storage diseases

Lysosomal storage diseases (LSDs) include approximately 70 distinct disorders that collectively account for 14% of all inherited metabolic diseases. LSDs are caused by mutations in various enzymes/proteins that disrupt lysosomal function, which impairs macromolecule degradation following endosome-ly...

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Veröffentlicht in:Front Neurosci
Hauptverfasser: Bosch, Megan E., Kielian, Tammy
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627351/
https://ncbi.nlm.nih.gov/pubmed/26578874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2015.00417
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