Novel roles of TMEM100: inhibition metastasis and proliferation of hepatocellular carcinoma

Transmembrane protein 100 (TMEM100) was activated by ALK1/TGF-β signaling. We found that TMEM100 was decreased in hepatocellular carcinoma (HCC) tissues and in highly metastatic cell lines. Overexpressed of TMEM100 inhibited invasion, migration and proliferation. Low levels of TMEM100 were associate...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Ou, Dipeng, Yang, Hao, Hua, Dong, Xiao, Shuai, Yang, Lianyue
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2015
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627315/
https://ncbi.nlm.nih.gov/pubmed/25978032
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