SNAI2/Slug gene is silenced in prostate cancer and regulates neuroendocrine differentiation, metastasis-suppressor and pluripotency gene expression

Prostate Cancer (PCa)-related deaths are mostly due to metastasization of poorly differentiated adenocarcinomas often endowed with neuroendocrine differentiation (NED) areas. The SNAI2/Slug gene is a major regulator of cell migration and tumor metastasization. We here assessed its biological signifi...

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Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Esposito, Silvia, Russo, Marco V., Airoldi, Irma, Tupone, Maria Grazia, Sorrentino, Carlo, Barbarito, Giulia, Di Meo, Serena, Di Carlo, Emma
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2015
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627296/
https://ncbi.nlm.nih.gov/pubmed/25686823
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