Phase I/II clinical trial of dendritic-cell based immunotherapy (DCVAC/PCa) combined with chemotherapy in patients with metastatic, castration-resistant prostate cancer

PURPOSE: We conducted an open-label, single-arm Phase I/II clinical trial in metastatic CRPC (mCRPC) patients eligible for docetaxel combined with treatment with autologous mature dendritic cells (DCs) pulsed with killed LNCaP prostate cancer cells (DCVAC/PCa). The primary and secondary endpoints we...

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Udgivet i:Oncotarget
Main Authors: Podrazil, Michal, Horvath, Rudolf, Becht, Etienne, Rozkova, Daniela, Bilkova, Pavla, Sochorova, Klara, Hromadkova, Hana, Kayserova, Jana, Vavrova, Katerina, Lastovicka, Jan, Vrabcova, Petra, Kubackova, Katerina, Gasova, Zdenka, Jarolim, Ladislav, Babjuk, Marek, Spisek, Radek, Bartunkova, Jirina, Fucikova, Jitka
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2015
Fag:
Clinical Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627245/
https://ncbi.nlm.nih.gov/pubmed/26078335
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