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The reciprocal regulation loop of Notch2 pathway and miR-23b in controlling gastric carcinogenesis

Gastric carcinoma is one of the most common malignancies and the third highest cause of global cancer-related death. Notch2 receptor intracellular domain (N2IC), the activated form of Notch2 receptor, enhances gastric carcinogenesis. MicroRNAs (miRNAs) act as either oncogenes or tumor suppressors in...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Huang, Tzu-Ting, Ping, Yueh-Hsin, Wang, An-Ming, Ke, Chia-Chi, Fang, Wen-Liang, Huang, Kuo-Hung, Lee, Hsin-Chen, Chi, Chin-Wen, Yeh, Tien-Shun
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627232/
https://ncbi.nlm.nih.gov/pubmed/26041881
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