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Clonal ordering of 17p and 5q allelic losses in Barrett dysplasia and adenocarcinoma.

Both 17p and 5q allelic losses appear to be involved in the pathogenesis or progression of many human solid tumors. In colon carcinogenesis, there is strong evidence that the targets of the 17p and 5q allelic losses are TP53, the gene encoding p53, and APC, respectively. It is widely accepted that 5...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Blount, P L, Meltzer, S J, Yin, J, Huang, Y, Krasna, M J, Reid, B J
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46271/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8475062/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.8.3221
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