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A bacterial regulatory RNA attenuates virulence, spread and human host cell phagocytosis
Staphylococcus aureus pathogenesis is directed by regulatory proteins and RNAs. We report the case of an RNA attenuating virulence and host uptake, possibly to sustain commensalism. A S. aureus sRNA, SprC (srn_3610), reduced virulence and bacterial loads in a mouse infection model. S. aureus deleted...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4627067/ https://ncbi.nlm.nih.gov/pubmed/26240382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv783 |
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