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Francisella tularensis type B ΔdsbA mutant protects against type A strain and induces strong inflammatory cytokine and Th1-like antibody response in vivo

Francisella tularensis subspecies tularensis is a highly virulent intracellular bacterial pathogen, causing the disease tularemia. However, a safe and effective vaccine for routine application against F. tularensis has not yet been developed. We have recently constructed the deletion mutants for the...

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Détails bibliographiques
Publié dans:Pathog Dis
Auteurs principaux: Straskova, Adela, Spidlova, Petra, Mou, Sherry, Worsham, Patricia, Putzova, Daniela, Pavkova, Ivona, Stulik, Jiri
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626617/
https://ncbi.nlm.nih.gov/pubmed/26253078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/femspd/ftv058
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