d-amino Acid Inhibits Biofilm but not New Bone Formation in an Ovine Model

BACKGROUND: Infectious complications of musculoskeletal trauma are an important factor contributing to patient morbidity. Biofilm-dispersive bone grafts augmented with d-amino acids (d-AAs) prevent biofilm formation in vitro and in vivo, but the effects of d-AAs on osteocompatibility and new bone fo...

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Bibliografske podrobnosti
izdano v:Clin Orthop Relat Res
Main Authors: Harmata, Andrew J., Ma, Yun, Sanchez, Carlos J., Zienkiewicz, Katarzyna J., Elefteriou, Florent, Wenke, Joseph C., Guelcher, Scott A.
Format: Artigo
Jezik:Inglês
Izdano: Springer US 2015
Teme:
Basic Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626484/
https://ncbi.nlm.nih.gov/pubmed/26201421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11999-015-4465-9
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