Antiphospholipid Antibodies Promote the Release of Neutrophil Extracellular Traps: A New Mechanism of Thrombosis in the Antiphospholipid Syndrome

OBJECTIVE: Antiphospholipid antibodies (aPL), especially those targeting beta-2-glycoprotein I (β(2)GPI), are well known to activate endothelial cells, monocytes, and platelets, with prothrombotic implications. In contrast, the interaction of aPL with neutrophils has not been extensively studied. Ne...

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Udgivet i:Arthritis Rheumatol
Main Authors: Yalavarthi, Srilakshmi, Gould, Travis J., Rao, Ashish N., Mazza, Levi F., Morris, Alexandra E., Núñez-Álvarez, Carlos, Hernández-Ramírez, Diego, Bockenstedt, Paula L., Liaw, Patricia C., Cabral, Antonio R., Knight, Jason S.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626310/
https://ncbi.nlm.nih.gov/pubmed/26097119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39247
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