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RNAi-mediated knockdown of the CLN3 gene inhibits proliferation and promotes apoptosis in drug-resistant ovarian cancer cells

CLN3 is a recently identified anti-apoptotic gene, which has been demonstrated to be highly expressed in a diverse range of cancer cell lines, including ovarian cancer. In the present study, RNA interference, mediated by a lentivirus expressing CLN3 short hairpin RNA (shRNA) was utilized to knockdow...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Mol Med Rep
मुख्य लेखकों: MAO, DONGWEI, CHE, JIANHUA, HAN, SHIYU, ZHAO, HONGHUI, ZHU, YUMEI, ZHU, HONG
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: D.A. Spandidos 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626189/
https://ncbi.nlm.nih.gov/pubmed/26299671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2015.4238
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