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Repeated intra-nigrostriatal injection of phorbol myristate acetate induces microglial senescence in adult rats

Phorbol myristate acetate (PMA), as a potent tumor promoter, may induce microglial senescence. The present study investigated the effect of PMA infection on microglial senescence. From 58 male Sprague-Dawley rats, 10 were randomly selected and divided into a PMA injection group, containing five rats...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: LIU, LIN, LUO, XIAO-GUANG, YU, HONG-MEI, FENG, YU, REN, YAN, YIN, YA-FU, SHANG, HONG, HE, ZHI-YI
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626136/
https://ncbi.nlm.nih.gov/pubmed/26459397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2015.4412
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