Loss- and Gain-of-Function Approaches Indicate a Dual Role Exerted by Regulatory T Cells in Pulmonary Paracoccidioidomycosis

Paracoccidioidomycosis (PCM), is a pulmonary fungal disease whose severity depends on the adequate development of T cell immunity. Although regulatory T (Treg) cells were shown to control immunity against PCM, deleterious or protective effects were described in different experimental settings. To cl...

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Vydáno v:PLoS Negl Trop Dis
Hlavní autoři: Bazan, Silvia B., Costa, Tania A., de Araújo, Eliseu Frank, Feriotti, Claudia, Loures, Flávio V., Pretel, Fernando D., Calich, Vera L. G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626087/
https://ncbi.nlm.nih.gov/pubmed/26512987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0004189
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