Phosphorylation of the Scc2 cohesin deposition complex subunit regulates chromosome condensation through cohesin integrity

The cohesion of replicated sister chromatids promotes chromosome biorientation, gene regulation, DNA repair, and chromosome condensation. Cohesion is mediated by cohesin, which is deposited on chromosomes by a separate conserved loading complex composed of Scc2 and Scc4 in Saccharomyces cerevisiae....

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Bibliographic Details
Published in:Mol Biol Cell
Main Authors: Woodman, Julie, Hoffman, Matthew, Dzieciatkowska, Monika, Hansen, Kirk C., Megee, Paul C.
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2015
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626061/
https://ncbi.nlm.nih.gov/pubmed/26354421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-03-0165
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