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Counterintuitive DNA Sequence Dependence in Supercoiling-Induced DNA Melting
The metabolism of DNA in cells relies on the balance between hybridized double-stranded DNA (dsDNA) and local de-hybridized regions of ssDNA that provide access to binding proteins. Traditional melting experiments, in which short pieces of dsDNA are heated up until the point of melting into ssDNA, h...
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| 發表在: | PLoS One |
|---|---|
| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Public Library of Science
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4625975/ https://ncbi.nlm.nih.gov/pubmed/26513573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141576 |
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