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Correlation between mutations and mRNA expression of APC and MUTYH genes: new insight into hereditary colorectal polyposis predisposition

BACKGROUND: Transcript dosage imbalance may influence the transcriptome. To gain insight into the role of altered gene expression in hereditary colorectal polyposis predisposition, in the present study we analyzed absolute and allele-specific expression (ASE) of adenomatous polyposis coli (APC) and...

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Bibliographische Detailangaben
Veröffentlicht in:J Exp Clin Cancer Res
Hauptverfasser: Aceto, Gitana Maria, Fantini, Fabiana, De Iure, Sabrina, Di Nicola, Marta, Palka, Giandomenico, Valanzano, Rosa, Di Gregorio, Patrizia, Stigliano, Vittoria, Genuardi, Maurizio, Battista, Pasquale, Cama, Alessandro, Curia, Maria Cristina
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4625907/
https://ncbi.nlm.nih.gov/pubmed/26511139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-015-0244-4
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