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RAPID AND RELIABLE HEALING OF CRITICAL SIZE BONE DEFECTS WITH GENETICALLY MODIFIED SHEEP MUSCLE

Large segmental defects in bone fail to heal and remain a clinical problem. Muscle is highly osteogenic, and preliminary data suggest that autologous muscle tissue expressing bone morphogenetic protein-2 (BMP-2) efficiently heals critical size defects in rats. Translation into possible human clinica...

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Detalhes bibliográficos
Publicado no:Eur Cell Mater
Main Authors: Liu, F., Ferreira, E., Porter, R.M., Glatt, V., Schinhan, M., Shen, Z., Randolph, M.A., Kirker-Head, C.A., Wehling, C., Vrahas, M.S., Evans, C.H., Wells, J.W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4625846/
https://ncbi.nlm.nih.gov/pubmed/26388615
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