Circulating ADAM17 Level Reflects Disease Activity in Proteinase-3 ANCA-Associated Vasculitis

ANCA-associated vasculitides are characterized by inflammatory destruction of small vessels accompanied by enhanced cleavage of membrane-bound proteins. One of the main proteases responsible for ectodomain shedding is disintegrin and metalloproteinase domain-containing protein 17 (ADAM17). Given its...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Bertram, Anna, Lovric, Svjetlana, Engel, Alissa, Beese, Michaela, Wyss, Kristin, Hertel, Barbara, Park, Joon-Keun, Becker, Jan U., Kegel, Johanna, Haller, Hermann, Haubitz, Marion, Kirsch, Torsten
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2015
Assuntos:
Clinical Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4625662/
https://ncbi.nlm.nih.gov/pubmed/25788529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014050477
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