Brain imaging and blood biomarker abnormalities in children with autosomal-dominant Alzheimer's disease: A cross-sectional Study

IMPORTANCE: Brain imaging and fluid biomarkers are characterized in children at risk for autosomal dominant Alzheimer disease (ADAD). OBJECTIVE: To characterize and compare structural magnetic resonance imaging (MRI), resting-state and task-dependent functional MRI, and plasma amyloid-β (Aβ) measure...

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Published in:JAMA Neurol
Main Authors: Quiroz, Y.T., Schultz, A., Chen, K., Protas, H., Brickhouse, M., Fleisher, A.S., Langbaum, J.B., Thiyyagura, P., Fagan, A.M., Shah, A.R., Muniz, M., Arboleda-Velasquez, JF, Munoz, C., Garcia, G., Acosta-Baena, N., Giraldo, M., Tirado, V., Ramirez, D., Tariot, PN, Dickerson, B.C., Sperling, R.A., Lopera, F., Reiman, E.M.
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4625544/
https://ncbi.nlm.nih.gov/pubmed/26121081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2015.1099
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