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NRROS Negatively Regulates Osteoclast Differentiation by Inhibiting RANKL-Mediated NF-κB and Reactive Oxygen Species Pathways

Negative regulator of reactive oxygen species (NRROS) is known to repress ROS generation in phagocytes. In this study, we examined the roles of NRROS in both osteoclasts and osteoblasts. Our results demonstrate that NRROS negatively regulates the differentiation of osteoclasts, but not osteoblasts....

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Publicat a:Mol Cells
Autors principals: Kim, Jung Ha, Kim, Kabsun, Kim, Inyoung, Seong, Semun, Kim, Nacksung
Format: Artigo
Idioma:Inglês
Publicat: Korean Society for Molecular and Cellular Biology 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4625072/
https://ncbi.nlm.nih.gov/pubmed/26442864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2015.0177
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