Activity and High-Order Effective Connectivity Alterations in Sanfilippo C Patient-Specific Neuronal Networks

Induced pluripotent stem cell (iPSC) technology has been successfully used to recapitulate phenotypic traits of several human diseases in vitro. Patient-specific iPSC-based disease models are also expected to reveal early functional phenotypes, although this remains to be proved. Here, we generated...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Canals, Isaac, Soriano, Jordi, Orlandi, Javier G., Torrent, Roger, Richaud-Patin, Yvonne, Jiménez-Delgado, Senda, Merlin, Simone, Follenzi, Antonia, Consiglio, Antonella, Vilageliu, Lluïsa, Grinberg, Daniel, Raya, Angel
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4625033/
https://ncbi.nlm.nih.gov/pubmed/26411903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.08.016
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