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SUMOylation of Argonaute-2 regulates RNA interference activity

Post-translational modification of substrate proteins by small ubiquitin-like modifier (SUMO) regulates a vast array of cellular processes. SUMOylation occurs through three sequential enzymatic steps termed E1, E2 and E3. Substrate selection can be determined through interactions between the target...

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Publicado en:Biochem Biophys Res Commun
Main Authors: Josa-Prado, Fernando, Henley, Jeremy M., Wilkinson, Kevin A.
Formato: Artigo
Idioma:Inglês
Publicado: Academic Press 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4624959/
https://ncbi.nlm.nih.gov/pubmed/26188511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2015.07.073
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