Ras Oncogene-Mediated Progressive Silencing of Extracellular Superoxide Dismutase in Tumorigenesis

Extracellular superoxide dismutase (SOD3) is a secreted enzyme that uses superoxide anion as a substrate in a dismutase reaction that results in the formation of hydrogen peroxide. Both of these reactive oxygen species affect growth signaling in cells. Although SOD3 has growth-supporting characteris...

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Bibliographic Details
Published in:Biomed Res Int
Main Authors: Cammarota, Francesca, de Vita, Gabriella, Salvatore, Marco, Laukkanen, Mikko O.
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4624945/
https://ncbi.nlm.nih.gov/pubmed/26550576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/780409
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