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Concentrations of cefixime in bronchial mucosa and sputum after three oral multiple dose regimens.

In a study of 58 patients the concentrations of cefixime, a new oral cephem antibiotic, in bronchial mucosa were 35-40% of the concentrations found in simultaneously collected serum samples. The antibiotic was often undetectable in sputum despite a highly sensitive assay.

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Bibliografische Detailangaben
Veröffentlicht in:Thorax
Hauptverfasser: Baldwin, D R, Andrews, J M, Ashby, J P, Wise, R, Honeybourne, D
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Publishing Group 1990
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC462490/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2382246/
https://ncbi.nlm.nih.govhttps://doi.org/10.1136/thx.45.5.401
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