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Molecular features of interaction between VEGFA and anti-angiogenic drugs used in retinal diseases: a computational approach

Anti-angiogenic agents are biological drugs used for treatment of retinal neovascular degenerative diseases. In this study, we aimed at in silico analysis of interaction of vascular endothelial growth factor A (VEGFA), the main mediator of angiogenesis, with binding domains of anti-angiogenic agents...

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Détails bibliographiques
Publié dans:Front Pharmacol
Auteurs principaux: Platania, Chiara B. M., Di Paola, Luisa, Leggio, Gian M., Romano, Giovanni L., Drago, Filippo, Salomone, Salvatore, Bucolo, Claudio
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4624855/
https://ncbi.nlm.nih.gov/pubmed/26578958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00248
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