Co-expression of Interleukin-15 Enhances the Protective Immune Responses Induced by Immunization with a Murine Malaria MVA-Based Vaccine Encoding the Circumsporozoite Protein

Malaria remains a major global public health problem with an estimated 200 million cases detected in 2012. Although the most advanced candidate malaria vaccine (RTS,S) has shown promise in clinical trials, its modest efficacy and durability have created uncertainty about the impact of RTS,S immuniza...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Parra, Marcela, Liu, Xia, Derrick, Steven C., Yang, Amy, Molina-Cruz, Alvaro, Barillas-Mury, Carolina, Zheng, Hong, Thao Pham, Phuong, Sedegah, Martha, Belmonte, Arnel, Litilit, Dianne D., Waldmann, Thomas A., Kumar, Sanjai, Morris, Sheldon L., Perera, Liyanage P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4624717/
https://ncbi.nlm.nih.gov/pubmed/26505634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141141
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