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Cell-based assays for screening androgen receptor ligands

The androgen receptor (AR, NR3C4), mediates the majority of androgen effects on target cells. The AR is activated following ligand binding that result in activation of target gene transcription. Several cell based model systems have been developed that allow sensitive detection and monitoring of ste...

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Détails bibliographiques
Publié dans:Semin Reprod Med
Auteurs principaux: Campana, Carmela, Pezzi, Vincenzo, Rainey, William E
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4624207/
https://ncbi.nlm.nih.gov/pubmed/26036905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0035-1552989
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