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Can Specific Protein-Lipid Interactions Stabilize an Active State of the Beta 2 Adrenergic Receptor?

G-protein-coupled receptors are eukaryotic membrane proteins with broad biological and pharmacological relevance. Like all membrane-embedded proteins, their location and orientation are influenced by lipids, which can also impact protein function via specific interactions. Extensive simulations tota...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Neale, Chris, Herce, Henry D., Pomès, Régis, García, Angel E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4624154/
https://ncbi.nlm.nih.gov/pubmed/26488656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.08.028
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