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A central role for HSC70 in regulating antigen trafficking and MHC class II presentation
Cells rely on multiple intracellular trafficking pathways to capture antigens for proteolysis. The resulting peptides bind to MHC class II molecules to promote CD4(+) T cell recognition. Endocytosis enhances the capture of extracellular and cell surface bound antigens for processing and presentation...
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| 發表在: | Mol Immunol |
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| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4623969/ https://ncbi.nlm.nih.gov/pubmed/25953005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2015.04.007 |
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