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Macronutrient deprivation modulates antigen trafficking and immune recognition through HSC70 accessibility
B lymphocytes exploit macroautophagy to capture cytoplasmic and nuclear proteins within autophagosomes. Fusion of autophagosomes with lysosomes and endosomes facilitates content proteolysis, with the resulting peptides selectively binding MHC class II molecules (MHCII) which are displayed for recogn...
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| Publicado no: | J Immunol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4324325/ https://ncbi.nlm.nih.gov/pubmed/25589076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402472 |
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