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A central role for HSC70 in regulating antigen trafficking and MHC class II presentation

Cells rely on multiple intracellular trafficking pathways to capture antigens for proteolysis. The resulting peptides bind to MHC class II molecules to promote CD4(+) T cell recognition. Endocytosis enhances the capture of extracellular and cell surface bound antigens for processing and presentation...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Immunol
Egile Nagusiak: Deffit, Sarah N., Blum, Janice S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623969/
https://ncbi.nlm.nih.gov/pubmed/25953005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2015.04.007
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