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Functions of dendritic-cell-bound IgE in allergy

Immunoglobulin E (IgE) functions as an Fc-receptor-bound antigen sensor for mast cells and basophils, the classical effector cells of allergy. A cell-bound IgE pool is formed when monomeric IgE binds to FcεRI, the high affinity IgE Fc receptor on these cells, and minor amounts of antigen are suffici...

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Bibliographic Details
Published in:Mol Immunol
Main Authors: Platzer, Barbara, Stout, Madeleine, Fiebiger, Edda
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623942/
https://ncbi.nlm.nih.gov/pubmed/26052071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2015.05.016
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