Evaluation of regulatory genetic variants in POU5F1 and risk of congenital heart disease in Han Chinese

OCT4 is a transcription factor of the POU family, which plays a key role in embryonic development and stem cell pluripotency. Previous studies have shown that Oct4 is required for cardiomyocyte differentiation in mice and its depletion could result in cardiac morphogenesis in embryo. However, whethe...

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Pubblicato in:Sci Rep
Autori principali: Lin, Yuan, Ding, Chenyue, Zhang, Kai, Ni, Bixian, Da, Min, Hu, Liang, Hu, Yuanli, Xu, Jing, Wang, Xiaowei, Chen, Yijiang, Mo, Xuming, Cui, Yugui, Shen, Hongbing, Sha, Jiahao, Liu, Jiayin, Hu, Zhibin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623744/
https://ncbi.nlm.nih.gov/pubmed/26507003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15860
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