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Structural determination of Virus protein U from HIV-1 by NMR in membrane environments

Virus protein U (Vpu) from HIV-1, a small membrane protein composed of a transmembrane helical domain and two α-helices in an amphipathic cytoplasmic domain, down modulates several cellular proteins, including CD4, BST-2/CD317/tetherin, NTB-A, and CCR7. The interactions of Vpu with these proteins in...

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Publicat a:Biochim Biophys Acta
Autors principals: Zhang, Hua, Lin, Eugene C., Das, Bibhuti B., Tian, Ye, Opella, Stanley J.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623708/
https://ncbi.nlm.nih.gov/pubmed/26362058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2015.09.008
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