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Alternative application of Tau protein in Creutzfeldt-Jakob disease diagnosis: Improvement for weakly positive 14-3-3 protein in the laboratory

The 14-3-3 protein has been used as a biomarker for the diagnosis of sporadic Creutzfeldt-Jakob disease (sCJD). However, weakly positive 14-3-3 leads to false positive results and an incorrect diagnosis. We attempted to use quantitative data for tau protein to provide an accurate diagnosis based on...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hyeon, Jae Wook, Kim, Su Yeon, Lee, Jeongmin, Park, Jun Sun, Hwang, Kyu Jam, Lee, Sol Moe, An, SeongSoo A., Lee, Myung Koo, Ju, Young Ran
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623667/
https://ncbi.nlm.nih.gov/pubmed/26507666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15283
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