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VEGF neutralizing aerosol therapy in primary pulmonary adenocarcinoma with K-ras activating-mutations
K-ras mutations promote angiogenesis in lung cancer and contribute to the drug resistance of cancer cells. It is not clear whether K-ras mutated adenocarcinomas are sensitive to anti-angiogenic therapy with monoclonal antibodies (mAbs) that target vascular endothelial growth factor (VEGF). Anti-angi...
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| Publicado no: | MAbs |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4623465/ https://ncbi.nlm.nih.gov/pubmed/25484066 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.34454 |
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