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Pluripotent cell derivation from male germline cells by suppression of Dmrt1 and Trp53

Diploid germ cells are thought to have pluripotency potential. We recently described a method to derive pluripotent stem cells (PSCs) from cultured spermatogonial stem cells (SSCs) by depleting Trp53 and Dmrt1, both of which are known suppressors of teratomas. In this study, we used this technique t...

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Bibliografiske detaljer
Udgivet i:J Reprod Dev
Main Authors: TANAKA, Takashi, KANATSU-SHINOHARA, Mito, HIROSE, Michiko, OGURA, Atsuo, SHINOHARA, Takashi
Format: Artigo
Sprog:Inglês
Udgivet: The Society for Reproduction and Development 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623154/
https://ncbi.nlm.nih.gov/pubmed/26227109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1262/jrd.2015-059
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