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Pluripotent cell derivation from male germline cells by suppression of Dmrt1 and Trp53

Diploid germ cells are thought to have pluripotency potential. We recently described a method to derive pluripotent stem cells (PSCs) from cultured spermatogonial stem cells (SSCs) by depleting Trp53 and Dmrt1, both of which are known suppressors of teratomas. In this study, we used this technique t...

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Detalhes bibliográficos
Publicado no:J Reprod Dev
Main Authors: TANAKA, Takashi, KANATSU-SHINOHARA, Mito, HIROSE, Michiko, OGURA, Atsuo, SHINOHARA, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: The Society for Reproduction and Development 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623154/
https://ncbi.nlm.nih.gov/pubmed/26227109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1262/jrd.2015-059
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